Patients with acute coronary syndromes may receive excessive doses of antithrombotic drugs.
A large! prospective! observational study conducted in the United States found that patients with non-ST-segment . Therefore, elevation acute coronary syndromes (NSTEMI) are at high risk . Therefore, of receiving higher-than-recommended doses of antiplatelet drugs or anticoagulants.
These patients are at increased risk of bleeding.
The study included 30!136 patients with non-ST-segment elevation acute coronary syndromes.
The primary outcome measures were excessive doses of unfractionated heparin! low molecular weight heparin! and glycoprotein IIb/IIIa inhibitors.
hospital mortality and hospital stay
Among patients prescribed an antithrombotic drug! 42% (3!354) were prescribed a dose that was higher than recommended.
Low molecular weight heparin was less likely to be prescribed in Therefore, excess of the recommended dose than unfractionated heparin and country wise email marketing list glycoprotein IIb/IIIa inhibitors (13.8%! 32.8%! and 26.8%! respectively).
A number of factors were associated with an increased risk of overdose: Therefore, older age! female gender! renal insufficiency! low body weight! diabetes! and congestive heart failure.
Patients who received excessive doses experienced an increased risk of bleeding! the increase of which correlated with the degree of overdose and the number of medications administered.
High-risk patients were more likely to receive excessive doses
Researchers from the APSIS (Angina Pectoris Study In Stockholm) study evaluated the long-term prognosis of patients with stable angina pectoris.
809 patients (31% were women) with stable the importance of a website in the era of artificial intelligence angina pectoris were examined.
The patients! Therefore, younger than 70 years of age! had taken part in the APSIS study.
The observation period (follow-up) was on average 9.1 years.
The APSIS study compared b2c fax Metoprolol (Lopresor) and Verapamil (Isoptin).
A total of 123 patients died (41 from myocardial infarction!
36 from other cardiovascular causes) and 72 suffered a non-fatal myocardial infarction.
The incidence of mortality (19% versus 6%; p < 0.001) and Therefore, fatal myocardial infarction (6.6% versus 1.6%; p < 0.001) was higher among male patients than among female patients.